Containment of antimicrobial drug-resistant gonorrhea

Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea.

The new superbug Neisseria gonorrhoeae has retained resistance to antimicrobials previously recommended for first-line treatment and has now demonstrated its capacity to develop resistance to the extended-spectrum cephalosporin, ceftriaxone, the last remaining option for first-line empiric treatment of gonorrhea. An era of untreatable gonorrhea may be approaching, which represents an exceedingl...

Antimicrobial Drug Use and Antibiotic-Resistant Bacteria

To the Editor: The article by Harris et al., published in the August 2007 issue of Emerging Infectious Diseases, examined the risk factors for selecting extended-spectrum β-lactamase–producing Enterobacteriaceae in intensive-care patients and found that exposure to piperacillin/tazobactam and vancomycin were independent risk factors (1). Although antimicrobial drug use has been historically lin...

Antimicrobial Effect of Multilayered Carbon Nanotubes on Multi-Drug-Resistant Pseudomonas aeruginosa

Background: Pseudomonas aeruginosa is the primary cause of infection with impaired defense mechanisms. P. aeruginosa commonly causes nosocomial infections and is the most common pathogen isolated from patients hospitalized for longer than 1 week. We examined the antimicrobial effect of multilayered carbon nanotubes on multi-drug-resistant. Materials and methods: In this research, 20 clinical i...

Cephalosporin-resistant gonorrhea in North America.

GONORRHEA HAS AFFECTED HUMANS FOR CENTUries and remains common. Worldwide, an estimated 106.1 million cases occur annually. In 2011, gonorrhea again was the second most commonly reported notifiable infection in the United States with 321 849 cases reported. Because gonorrhea often can be asymptomatic, the true disease burden may be closer to 700 000. Gonorrhea disproportionately affects racial,...

Antimicrobial resistance and the growing threat of drug-resistant tuberculosis.